Article
Analysis of HLA-G polymorphisms in couples with implantation failure.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 2012
Nardi Fabiola da Silva, Slowik Renata, Wowk Pryscilla Fanini, da Silva José Samuel, Gelmini Geórgia Fernanda, Michelon Tatiana Ferreira, Neumann Jorge, Bicalho Maria da Graça
Abstract excerpt
PROBLEM: HLA-G expression is related as an immune modulator of fetal-maternal tolerance, and its levels was correlated with pregnancy outcome. In a case-control study, we investigate the association between the genetic variability of the HLA-G gene and serum levels of soluble HLA-G in cases of embryo implantation failure. METHOD OF STUDY: Forty couples with at least two unsuccessful fresh embryo transfers...
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