Article
Dermal dendrocytes FXIIIa+ are essential antigen-presenting cells in indeterminate leprosy.
The American Journal of dermatopathology - 1 Apr 2015
de Alvarenga Lira Marcia Lanzoni, Pagliari Carla, de Lima Silva Aline Alves, de Andrade Heitor Franco, Duarte Maria Irma Seixas
Abstract excerpt
Indeterminate leprosy (IL) is the early phase of Hansen disease and reword (APCs). Langerhans cells and dermal dendrocytes FXIIIa positive (DDFXIIIa) are the major APCs in the skin and can be identified by the expression of CD1a and FXIIIa, respectively, by immunohistochemical techniques. Plasmacytoid dendritic cells (PDCs) are another type of dermal dendrocytes with a questionable antigen-presenting function and...
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