Article
Recruitment of dendritic cells in oral lichen planus.
The Journal of pathology - 1 Mar 2005
Santoro Amerigo, Majorana Alessandra, Roversi Luca, Gentili Francesca, Marrelli Simona, Vermi William, Bardellini Elena, Sapelli Pierluigi, Facchetti Fabio
Abstract excerpt
Using immunohistochemistry the presence of different dendritic cell (DC) subsets was analysed in 16 biopsies from patients with oral lichen planus (OLP). A significant increase of CD1a+/Langerin+ Langerhans cells, DC-SIGN+ DC and CD123+/BDCA2+ plasmacytoid DCs (PDCs) was found in the epithelium and in the stroma of OLP biopsies compared to normal oral mucosa. A proportion of DCs were mature DC-LAMP+ and expressed...
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