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Article

Loss of the lac operon contributes to Salmonella invasion of epithelial cells through derepression of flagellar synthesis.

Current microbiology - 1 Mar 2015

Jiang Lingyan, Ni Zhiwei, Wang Lei, Feng Lu, Liu Bin

Abstract excerpt

Salmonella, a genus that is closely related to Escherichia coli, includes many pathogens of humans and other animals. A notable feature that distinguishes Salmonella from E. coli is lactose negativity, because the lac operon is lost in most Salmonella genomes. Here, we expressed the lac operon in Salmonella enterica serovar Typhimurium and compared the virulence of the Lac(+) strain to that of the wild-type...

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PMID: 25362512
DOI: 10.1007/s00284-014-0720-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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