Article
Biological and virulence characteristics of the YqhC mutant of Salmonella.
Microbiology and immunology - 1 Dec 2011
Eakley Nicholas M, Bochsler Philip N, Gopal Reddy P, Chopra Ashok K, Fadl Amin A
Abstract excerpt
Previous work by the present authors indicated a murein lipoprotein mutant of Salmonella shows a marked down-regulation in expression of yqhC. Because YqhC is a putative DNA-binding protein, it is likely involved in modulation of Salmonella genes. Deletion of yqhC renders Salmonella defective in invasion of intestinal epithelial cells, motility, and induction of cytotoxicity. In the present study, further...
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