Article
Mathematical model of platelet turnover in thrombocytopenic and nonthrombocytopenic preterm neonates.
American journal of physiology. Heart and circulatory physiology - 1 Jan 2015
Kulshrestha Mudit, Sola-Visner Martha, Widness John A, Veng-Pedersen Peter, Mager Donald E
Abstract excerpt
Neonatal thrombocytopenia affects 22-35% of all neonates admitted to neonatal intensive care units. The purpose of this study was to develop a mathematical model for characterizing platelet (PLT) kinetics in thrombocytopenic preterm neonates. Immature PLT fraction (IPF) and PLT counts were measured for up to 35 days after birth in 27 very low birth weight preterm neonates. PLT transfusions were administered to 8...
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