Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prothrombotic SERPINC1 gene polymorphism may affect heparin sensitivity among different ethnicities of Chinese patients receiving heart surgery.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Nov 2015

Wang Jiang, Ma Hai-Ping, Ti Ai Lai Ti Ta Lai, Zhang Yong-Qiang, Zheng Hong

Abstract excerpt

The purpose of this study was to investigate a possible correlation between single-nucleotide polymorphisms (SNPs) of the antithrombin (gene, SERPINC1, and perioperative sensitivity to heparin in patients receiving heart surgery. The SERPINC1 genotype and allele frequency, coagulation parameters 24 hours before and after surgery, and clinical findings were compared among 3 ethnic groups, Han, Uighur, and Kazakh,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Coagulation

Share to Cardiac Surgical Procedures

Share to Gene Frequency

Share to Heparin

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 25361738
DOI: 10.1177/1076029614556744

Genes

SERPINC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prothrombotic SERPINC1 gene polymorphism may affect heparin sensitivity among different ethnicities of Chinese patients receiving heart surgery.PMID 25361738Read ↗

Identification of a new SERPINC1 mutation in a Kazak family that alters the heparin binding capacity of antithrombin.Semantic proximity Read ↗

Subtypes of SERPINC1 mutations and the thrombotic phenotype of inherited antithrombin deficient individuals in Chinese Han population.Semantic proximity Read ↗

Molecular basis of SERPINC1 mutations in Japanese patients with antithrombin deficiencySemantic proximity Read ↗

A common missense variant in exon 5 of antithrombin gene (SERPINC1) in Indian patients with thrombosisSemantic proximity Read ↗

Association between gene polymorphisms and initial warfarin therapy in patients after heart valve surgery.Semantic proximity Read ↗

Effect of gene polymorphism on bleeding complications in Chinese Han patients taking warfarin.Semantic proximity Read ↗

[Clinical and genetic analysis of pulmonary embolism induced by a novel gene mutation of the antithrombin Ⅲ gene].Semantic proximity Read ↗

Novel Mutation p.Asp374Val of SERPINC1 in a Turkish Family with Inherited Antithrombin DeficiencySemantic proximity Read ↗

Impact of genetic variation on perioperative bleeding.Semantic proximity Read ↗

The influence of genetic polymorphisms and interacting drugs on initial response to warfarin in Chinese patients with heart valve replacement.Semantic proximity Read ↗

Predictive genomics of adverse events after cardiac surgery.Semantic proximity Read ↗

Genetic influence on bleeding and over-anticoagulation risk in patients undergoing warfarin treatment after heart valve replacements.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.