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Article

Identification of a new SERPINC1 mutation in a Kazak family that alters the heparin binding capacity of antithrombin.

Thrombosis research - 1 Dec 2014

Zheng Hong, Ma Hai-Ping, Xu Wei-fang, Zhang Yong-Qiang, Wu Jian-jiang, Wang Jiang

Abstract excerpt

INTRODUCTION: Given its central role in mediating heparin-induced anti-coagulation, antithrombin (AT) gene mutations may result in heparin resistance. This study investigates the relationship between familial AT gene mutations and tolerance to heparin. METHODS: The medical history of a male patient with heparin resistance who received heart surgery and six of his family members was reviewed. Activated partial...

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Source

Identifiers

PMID: 25312341
DOI: 10.1016/j.thromres.2014.09.034

Genes

SERPINC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a new SERPINC1 mutation in a Kazak family that alters the heparin binding capacity of antithrombin.PMID 25312341Read ↗

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