Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications.

Oncotarget - 15 Dec 2014

Oikonomou Eftychia, Koustas Evangelos, Goulielmaki Maria, Pintzas Alexander

Abstract excerpt

As the increased knowledge of tumour heterogeneity and genetic alterations progresses, it exemplifies the need for further personalized medicine in modern cancer management. Here, the similarities but also the differential effects of RAS and BRAF oncogenic signalling are examined and further impl...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to BRAF gene
Share to Genes, ras

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms

Share to Proto-Oncogene Proteins B-raf

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 25361007
DOI: 10.18632/oncotarget.2555
PMCID: PMC4322985

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25361007-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications.PMID 25361007Read ↗

KRAS and BRAF: drug targets and predictive biomarkers.Semantic proximity Read ↗

Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid CancersSemantic proximity Read ↗

Targeting the MAPK–RAS–RAF signaling pathway in cancer therapySemantic proximity Read ↗

Targeting the ERK/MAPK Pathway in Cancer: Oncogenic Mechanisms, Therapeutic Resistance, and Emerging Gene-Based StrategiesSemantic proximity Read ↗

RAS and BRAF in the foreground for non-small cell lung cancer and colorectal cancer: Similarities and main differences for prognosis and therapies.Semantic proximity Read ↗

RAS: Circuitry and therapeutic targeting.Semantic proximity Read ↗

New advances in the clinical management of RAS and BRAF mutant colorectal cancer patients.Semantic proximity Read ↗

BRAFV600E: implications for carcinogenesis and molecular therapy.Semantic proximity Read ↗

The importance of Ras in drug resistance in cancerSemantic proximity Read ↗

The current state of the art and future trends in RAS-targeted cancer therapies.Semantic proximity Read ↗

[Targeting the RAS signalling pathway in cancer].Semantic proximity Read ↗

RAS pathway regulation in melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.