Article
Screening of Mycobacterium avium subsp. paratuberculosis mutants for attenuation in a bovine monocyte-derived macrophage model.
Frontiers in cellular and infection microbiology - 1 Jan 2014
Lamont Elise A, Talaat Adel M, Coussens Paul M, Bannantine John P, Grohn Yrjo T, Katani Robab, Li Ling-ling, Kapur Vivek, Sreevatsan Srinand
Abstract excerpt
Vaccination remains a major tool for prevention and progression of Johne's disease, a chronic enteritis of ruminants worldwide. Currently there is only one licensed vaccine within the United States and two vaccines licensed internationally against Johne's disease. All licensed vaccines reduce fecal shedding of Mycobacterium avium subsp. paratuberculosis (MAP) and delay disease progression. However, there are no...
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