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Article

One small step for a yeast--microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation.

PLoS pathogens - 1 Oct 2014

Brunke Sascha, Seider Katja, Fischer Daniel, Jacobsen Ilse D, Kasper Lydia, Jablonowski Nadja, Wartenberg Anja, Bader Oliver, Enache-Angoulvant Adela, Schaller Martin, d'Enfert Christophe, Hube Bernhard

Abstract excerpt

Candida glabrata is one of the most common causes of candidemia, a life-threatening, systemic fungal infection, and is surpassed in frequency only by Candida albicans. Major factors contributing to the success of this opportunistic pathogen include its ability to readily acquire resistance to ant...

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Identifiers

PMID: 25356907
DOI: 10.1371/journal.ppat.1004478
PMCID: PMC4214790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25356907-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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