Article
Experimental Evolution of Candida by Serial Passaging in Host Cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Graf Katja, Hube Bernhard, Brunke Sascha
Abstract excerpt
Experimental evolution is an experiment class of its own; instead of requiring an a priori hypothesis, the genetic adaptation of microbes to defined environments tells us about the underlying pathways and mechanisms. Such experiments are often deceptively simple in their design, based on a single abiotic stressor and what is in essence a long-term continuous culture. However, they generally provide a starting...
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