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Advanced Feeder-Free Generation of Induced Pluripotent Stem Cells Directly From Blood Cells

29 Oct 2014

Abstract excerpt

Generation of validated human induced pluripotent stem cells (iPSCs) for biobanking is essential for exploring the full potential of iPSCs in disease modeling and drug discovery. Peripheral blood mononuclear cells (PBMCs) are attractive targets for reprogramming, because blood is collected by a routine clinical procedure and is a commonly stored material in biobanks. Generation of iPSCs from blood cells has...

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PMID: 25355732
DOI: 10.5966/sctm.2014-0113

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