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Article

T helper cell 2 immune skewing in pregnancy/early life: chemical exposure and the development of atopic disease and allergy

29 Oct 2014

Abstract excerpt

During the last 50 years there has been a significant increase in Western societies of atopic disease and associated allergy. The balance between functional subpopulations of T helper cells (Th) determines the quality of the immune response provoked by antigen. One such subpopulation - Th2 cells - is associated with the production of IgE antibody and atopic allergy, whereas, Th1 cells antagonize IgE responses and...

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PMID: 25354210
DOI: 10.1111/bjd.13497

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