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Epigenetic regulation of asthma and allergic disease

28 May 2014

Abstract excerpt

Epigenetics of asthma and allergic disease is a field that has expanded greatly in the last decade. Previously thought only in terms of cell differentiation, it is now evident the epigenetics regulate many processes. With T cell activation, commitment toward an allergic phenotype is tightly regulated by DNA methylation and histone modifications at the Th2 locus control region. When normal epigenetic control is...

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PMID: 24932182
DOI: 10.1186/1710-1492-10-27

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