Association analysis between breast cancer genetic variants and mammographic density in a large population-based study (Determinants of Density in Mammographies in Spain) identifies susceptibility loci in TOX3 gene.

doi:10.1016/j.ejca.2012.08.026

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Article

Association analysis between breast cancer genetic variants and mammographic density in a large population-based study (Determinants of Density in Mammographies in Spain) identifies susceptibility loci in TOX3 gene.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2013

Fernandez-Navarro Pablo, Pita Guillermo, Santamariña Carmen, Moreno María Pilar, Vidal Carmen, Miranda-García Josefa, Ascunce Nieves, Casanova Francisco, Collado-García Francisca, Herráez Belen, González-Neira Anna, Benítez Javier, Pollán Marina

Abstract excerpt

BACKGROUND: Mammographic density (MD) is regarded as an intermediate phenotype in breast cancer development. This association study investigated the influence of 14 breast cancer susceptibility loci identified through previous genome-wide association studies on MD among the participants in the "Determinants of Density in Mammographies in Spain" (DDM-Spain) study. METHODS: Our study covered a total of 3348...

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Identifiers

PMID: 23021931
DOI: 10.1016/j.ejca.2012.08.026

Genes

TOX3
FGFR2
LSP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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