Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Matrix metalloproteinases and genetic mouse models in cancer research: a mini-review.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2015

Wieczorek Edyta, Jablonska Ewa, Wasowicz Wojciech, Reszka Edyta

Abstract excerpt

Carcinogenesis is a multistep and also a multifactorial process that involves agents like genetic and environmental factors. Matrix metalloproteinases (MMPs) are major proteolytic enzymes which are involved in cancer cell migration, invasion, and metastasis. Genetic variations in genes encoding the MMPs were shown in human studies to influence cancer risk and phenotypic features of a tumor. The complex role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenesis
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to Matrix Metalloproteinases

Share to Mice, Knockout

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25352026
DOI: 10.1007/s13277-014-2747-6
PMCID: PMC4315474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Matrix metalloproteinases and genetic mouse models in cancer research: a mini-review.PMID 25352026Read ↗

Protective roles of matrix metalloproteinases: from mouse models to human cancer.Semantic proximity Read ↗

Matrix Metalloproteinases and Cancer - Roles in Threat and TherapySemantic proximity Read ↗

Matrix Metalloproteinases and Their Role in Oncogenesis: A ReviewSemantic proximity Read ↗

Roles of matrix metalloproteinases in cancer progression and their pharmacological targetingSemantic proximity Read ↗

Insights Into the Role of Matrix Metalloproteinases in Cancer and its Various Therapeutic Aspects: A ReviewSemantic proximity Read ↗

Matrix metalloproteinases in cancerSemantic proximity Read ↗

Update of human and mouse matrix metalloproteinase familiesSemantic proximity Read ↗

Cancer Susceptibility Models in Protease-Deficient Mice.Semantic proximity Read ↗

Matrix Metalloproteinase-2 (MMP-2): As an Essential Factor in Cancer ProgressionSemantic proximity Read ↗

Loss of collagenase-2 confers increased skin tumor susceptibility to male mice.Semantic proximity Read ↗

Unraveling metalloproteinase function in skeletal biology and disease using genetically altered miceSemantic proximity Read ↗

Physiological roles of matrix metalloproteinases: implications for tumor growth and metastasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.