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Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity

24 Oct 2014

Abstract excerpt

Cancer stem cells (CSCs) are considered to be the cause of tumor initiation, metastasis and recurrence. Additionally, CSCs are responsible for the failure of chemotherapy and radiotherapy. The isolation and identification of CSCs is crucial for facilitating the monitoring, therapy or prevention of cancer. We aimed to identify esophageal squamous cell carcinoma (ESCC) stem-like cells, the epigenetic mechanism and...

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PMID: 25351876
DOI: 10.3892/or.2014.3569

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