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DEAD-box helicase 27 enhances stem cell-like properties with poor prognosis in breast cancer

6 Aug 2021

Abstract excerpt

BACKGROUND: Although the rapid development of diagnosis and treatment has improved prognosis in early breast cancer, challenges from different therapeutic response remain due to breast cancer heterogeneity. DEAD-box helicase 27 (DDX27) had been proved to influence ribosome biogenesis and identified as a promoter in gastric and colorectal cancer associated with stem cell-like properties, while the impact of DDX27...

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PMID: 34362383
DOI: 10.1186/s12967-021-03011-0

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