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Article

CXCR7 stimulates MAPK signaling to regulate hepatocellular carcinoma progression.

Cell death & disease - 23 Oct 2014

Lin L, Han M-M, Wang F, Xu L-L, Yu H-X, Yang P-Y

Abstract excerpt

The CXCL12/CXCR4 axis has been posited widely to have significant roles in many primary tumors and metastases. It is known that CXCR7 can also be engaged by CXCL12, but the exact function of CXCR7 is controversial. This prompted us to investigate the expression, specific function and signal transduction of CXCR7 in hepatocellular carcinoma (HCC). In this study, CXCR7 and CXCR4 were differentially expressed in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25341042
DOI: 10.1038/cddis.2014.392
PMCID: PMC4649507

Genes

CXCL12
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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