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Article

Relationship of DNA Methylation and Gene Expression in Idiopathic Pulmonary Fibrosis

21 Oct 2014

Abstract excerpt

RATIONALE: Idiopathic pulmonary fibrosis (IPF) is an untreatable and often fatal lung disease that is increasing in prevalence and is caused by complex interactions between genetic and environmental factors. Epigenetic mechanisms control gene expression and are likely to regulate the IPF transcriptome. OBJECTIVES: To identify methylation marks that modify gene expression in IPF lung. METHODS: We assessed DNA...

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Share to Epigenetics and DNA Methylation
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PMID: 25333685
DOI: 10.1164/rccm.201408-1452oc

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