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Article

Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction

1 Jun 2014

Abstract excerpt

A systematic quantitative analysis of temporal changes in host and viral proteins throughout the course of a productive infection could provide dynamic insights into virus-host interaction. We developed a proteomic technique called "quantitative temporal viromics" (QTV), which employs multiplexed tandem-mass-tag-based mass spectrometry. Human cytomegalovirus (HCMV) is not only an important pathogen but a paradigm...

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PMID: 24906157
DOI: 10.1016/j.cell.2014.04.028

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