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Enhanced tuberculosis outbreak investigation using whole genome sequencing and IGRA

16 Oct 2014

Abstract excerpt

Whole genome sequencing (WGS) is a new powerful technology for characterisation of bacterial genomes and has been used successfully to investigate Mycobacterium tuberculosis isolates associated with tuberculosis (TB) outbreaks and to elucidate mutations conferring drug resistance [1–6]. Enhanced contact investigation and improved diagnosis and treatment of latent TB infection (LTBI) are an important strategy for...

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PMID: 25323236
DOI: 10.1183/09031936.00125914

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