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Article

'Division of labour' in response to host oxidative burst drives a fatal Cryptococcus gattii outbreak.

Nature communications - 17 Oct 2014

Voelz Kerstin, Johnston Simon A, Smith Leanne M, Hall Rebecca A, Idnurm Alexander, May Robin C

Abstract excerpt

Cryptococcus gattii is an emerging intracellular pathogen and the cause of the largest primary outbreak of a life-threatening fungal disease in a healthy population. Outbreak strains share a unique mitochondrial gene expression profile and an increased ability to tubularize their mitochondria within host macrophages. However, the underlying mechanism that causes this lineage of C. gattii to be virulent in...

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Identifiers

PMID: 25323068
DOI: 10.1038/ncomms6194
PMCID: PMC4208095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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