Article
Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii.
mBio - 1 Sept 2015
Farrer Rhys A, Desjardins Christopher A, Sakthikumar Sharadha, Gujja Sharvari, Saif Sakina, Zeng Qiandong, Chen Yuan, Voelz Kerstin, Heitman Joseph, May Robin C, Fisher Matthew C, Cuomo Christina A
Abstract excerpt
UNLABELLED: Cryptococcus gattii is a fungal pathogen of humans, causing pulmonary infections in otherwise healthy hosts. To characterize genomic variation among the four major lineages of C. gattii (VGI, -II, -III, and -IV), we generated, annotated, and compared 16 de novo genome assemblies, including the first for the rarely isolated lineages VGIII and VGIV. By identifying syntenic regions across assemblies, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.