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Article

Novel nonsense mutation of BRCA2 gene in a Moroccan man with familial breast cancer.

African health sciences - 1 Jun 2014

Guaoua Soukaina, Ratbi Ilham, Lyahyai Jaber, El Alaoui Siham Chafai, Laarabi Fatima-Zahra, Sefiani Abdelaziz

Abstract excerpt

BACKGROUND: Breast cancer is the most common cancer in women worldwide. About 5 to 10% of cases are due to an inherited predisposition in two major genes, BRCA1 and BRCA2, transmitted as an autosomal dominant form. Male breast cancer is rare and is mainly due to BRCA2 than BRCA1 germline mutations. OBJECTIVE: Molecular study of BRCA2 gene in man with familial breast cancer. METHODS: PCR and direct sequencing of...

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Source

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Identifiers

PMID: 25320599
DOI: 10.4314/ahs.v14i2.25
PMCID: PMC4196389

Genes

BRCA2
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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