Article
Phenotypic modulation of smooth muscle cells in lymphoedema.
The British journal of dermatology - 1 Jan 2015
Ogata F, Fujiu K, Koshima I, Nagai R, Manabe I
Abstract excerpt
BACKGROUND: Lymphoedema is a debilitating progressive condition that is frequently observed following cancer surgery and severely restricts quality of life. Although it is known that lymphatic dysfunction and obstruction underlie lymphoedema, the pathogenic mechanism is poorly understood. Smooth muscle cells (SMCs) play pivotal roles in the pathogenesis of various vascular diseases, including atherosclerosis....
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