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Article

Frequent occurrence of gastric cancer in Asian kindreds with Li-Fraumeni syndrome.

Clinical genetics - 1 Nov 2015

Ariffin H, Chan A S L, Oh L, Abd-Ghafar S, Ong G B, Mohamed M, Razali H, Juraida E, Teo S H, Karsa M, Shamsani J, Hainaut P

Abstract excerpt

Type of cancer and age of onset in individuals with inherited aberrations in the tumour suppressor gene TP53 are variable, possibly influenced by genetic modifiers and different environmental exposure. Since 2009, the modified Chompret criteria (MCC) have been used to identify individuals for TP5...

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Source

Identifiers

PMID: 25318593
DOI: 10.1111/cge.12525

Genes

MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25318593-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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