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Article

Targeting the Root Cause of Cystic Fibrosis.

Current drug targets - 1 Jan 2015

Trescott Laura, Holcomb Joshua, Spellmon Nicholas, Mcleod Cathy, Aljehane Leala, Sun Fei, Li Chunying, Yang Zhe

Abstract excerpt

Cystic Fibrosis (CF) is a serious genetic condition caused by CF transmembrane conductance regulator (CFTR) mutation. CF patients have shortened lifespan due to airway obstruction, infection, and end-stage lung failure. However, recent development in CF therapy suggests a brighter future for CF p...

Read the complete abstract on PubMed

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Share to Cell Membrane
Share to Cystic Fibrosis
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CFTR gene

Share to Genetic Therapy

Share to Mutation

Share to Protein Transport

Source

Identifiers

PMID: 25316272
DOI: 10.2174/1389450115999141030144247

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25316272-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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