Article
Progress towards next-generation therapeutics for cystic fibrosis.
Future medicinal chemistry - 1 Jun 2014
O'Neil Deborah A, Fraser-Pitt Douglas
Abstract excerpt
Cystic fibrosis (CF) is the most common inherited genetic condition amongst Caucasian ethnicities, affecting 1 in 2500 live births. There remains a significant unmet medical need for more and better therapies for this chronic, degenerative condition, in particular those that address the respiratory dysfunction and respiratory infections that characterise CF. CF is caused by mutations in the cystic transmembrane...
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