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Article

Changing the Paradigm - Treating the Basic Defect in Cystic Fibrosis.

Indian journal of pediatrics - 1 Aug 2015

Guglani Lokesh

Abstract excerpt

Since the first description of Cystic fibrosis (CF) more than 75 y ago, significant advances have been made in understanding its pathogenesis and in developing specific therapies. The pace of these developments was further accelerated after the discovery of CF gene in 1989 and since then, CF has been transformed from being a pediatric illness into a chronic life-limiting genetic disorder with survival up to the...

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PMID: 26077199
DOI: 10.1007/s12098-015-1786-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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