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A curated C. difficile strain 630 metabolic network: prediction of essential targets and inhibitors

14 Oct 2014

Abstract excerpt

BACKGROUND: Clostridium difficile is the leading cause of hospital-borne infections occurring when the natural intestinal flora is depleted following antibiotic treatment. Current treatments for Clostridium difficile infections present high relapse rates and new hyper-virulent and multi-resistant strains are emerging, making the study of this nosocomial pathogen necessary to find novel therapeutic targets....

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PMID: 25315994
DOI: 10.1186/s12918-014-0117-z

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