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Article

Efficient replication of Epstein–Barr virus in stratified epithelium in vitro

13 Oct 2014

Abstract excerpt

Epstein-Barr virus is a ubiquitous human herpesvirus associated with epithelial and lymphoid tumors. EBV is transmitted between human hosts in saliva and must cross the oral mucosal epithelium before infecting B lymphocytes, where it establishes a life-long infection. The latter process is well understood because it can be studied in vitro, but our knowledge of infection of epithelial cells has been limited by...

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PMID: 25313069
DOI: 10.1073/pnas.1400818111

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