Article
Patterns and dynamics of genetic diversity in Plasmodium falciparum: what past human migrations tell us about malaria.
Parasitology international - 1 Jun 2015
Mita Toshihiro, Jombart Thibaut
Abstract excerpt
Plasmodium falciparum is the main agent of malaria, one of the major human infectious diseases affecting millions of people worldwide. The genetic diversity of P. falciparum populations is an essential factor in the parasite's ability to adapt to changes in its environment, enabling the development of drug resistance and the evasion from the host immune system through antigenic variation. Therefore,...
Topics
- Africa
- Antigenic Variation
- Environment
- Genetic Variation
- Human Migration
- Humans
- Malaria, Falciparum
- Plasmodium falciparum
- Polymorphism, Genetic