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Short Communication: Nitazoxanide Inhibits HIV Viral Replication in Monocyte-Derived Macrophages

10 Oct 2014

Abstract excerpt

We document the anti-HIV activity of nitazoxanide (NTZ), the first member of the thiazolide class of antiinfective drugs, originally effective against enteritis caused by Cryptosporidium parvum and Giardia lamblia. NTZ has been administered extensively worldwide, with no severe toxicities associated with its use. Here, we show for the first time that NTZ decreases HIV-1 replication in monocyte-derived macrophages...

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PMID: 25303025
DOI: 10.1089/aid.2014.0015

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