Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In Vitro and In Vivo Anti-Schistosomal Activity of the Alkylphospholipid Analog Edelfosine

10 Oct 2014

Abstract excerpt

BACKGROUND: Schistosomiasis is a parasitic disease caused by trematodes of the genus Schistosoma. Five species of Schistosoma are known to infect humans, out of which S. haematobium is the most prevalent, causing the chronic parasitic disease schistosomiasis that still represents a major problem of public health in many regions of the world and especially in tropical areas, leading to serious manifestations and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Parasites and Host Interactions
Share to Research on Leishmaniasis Studies
Share to Sphingolipid Metabolism and Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25302497
DOI: 10.1371/journal.pone.0109431

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In Vitro and In Vivo Anti-Schistosomal Activity of the Alkylphospholipid Analog EdelfosinePMID 25302497Read ↗

<i>Schistosoma mansoni</i> lysine specific demethylase 1 (SmLSD1) is a druggable target involved in parasite survival, oviposition and stem cell proliferationSemantic proximity Read ↗

Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changesSemantic proximity Read ↗

Artemisitene protected against murine schistosomiasis japonica through anti-parasite activity and immune regulationSemantic proximity Read ↗

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive SystemsSemantic proximity Read ↗

Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in <i>Schistosoma mansoni</i>Semantic proximity Read ↗

Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activitiesSemantic proximity Read ↗

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targetsSemantic proximity Read ↗

Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo.Semantic proximity Read ↗

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targetsSemantic proximity Read ↗

JQ-1 ameliorates schistosomiasis liver granuloma in mice by suppressing male and female reproductive systems and egg development of <i>Schistosoma japonicum</i>Semantic proximity Read ↗

Transcriptional phenotype of the anti-parasitic benzodiazepine meclonazepam on the blood fluke <i>Schistosoma mansoni</i>Semantic proximity Read ↗

IPSE, a parasite-derived host immunomodulatory protein, is a promising therapeutic for hemorrhagic cystitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.