Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo.

Experimental parasitology - 1 Jan 2011

Manneck Theresia, Braissant Olivier, Ellis William, Keiser Jennifer

Abstract excerpt

Recent studies have shown that mefloquine (MQ) reveals interesting antischistosomal properties. We examined the antischistosomal activities of the erythro and threo isomers and racemates of MQ on newly transformed schistosomula (NTS) and adult Schistosoma mansoni in vitro and in mice harbouring adult S. mansoni. The in vitro effects in the presence and absence of haemin were monitored by means of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calorimetry
Share to Drug Evaluation, Preclinical

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mefloquine

Share to Microscopy, Electron, Scanning

Share to Schistosoma mansoni

Share to Schistosomiasis mansoni

Share to Stereoisomerism

Source

Identifiers

PMID: 20732321
DOI: 10.1016/j.exppara.2010.08.011

Genes

NTS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo.PMID 20732321Read ↗

Artemisitene protected against murine schistosomiasis japonica through anti-parasite activity and immune regulationSemantic proximity Read ↗

Phenotypic Screening of Small Molecules with Antimalarial Activity for Three Different Parasitic Life Stages.Semantic proximity Read ↗

Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive SystemsSemantic proximity Read ↗

In Vitro and In Vivo Anti-Schistosomal Activity of the Alkylphospholipid Analog EdelfosineSemantic proximity Read ↗

Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomalSemantic proximity Read ↗

Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents.Semantic proximity Read ↗

Transcriptional phenotype of the anti-parasitic benzodiazepine meclonazepam on the blood fluke <i>Schistosoma mansoni</i>Semantic proximity Read ↗

Identification of Antimalarial Inhibitors Using Late-Stage Gametocytes in a Phenotypic Live/Dead Assay.Semantic proximity Read ↗

The Spiroindolone Drug Candidate NITD609 Potently Inhibits Gametocytogenesis and Blocks Plasmodium falciparum Transmission to Anopheles Mosquito VectorSemantic proximity Read ↗

Transcriptional phenotype of the anti-parasitic benzodiazepine meclonazepam on the blood fluke Schistosoma mansoni.Semantic proximity Read ↗

Diminazene Aceturate (Berenil) Modulates the Host Cellular and Inflammatory Responses to Trypanosoma congolense InfectionSemantic proximity Read ↗

A novel cell-free method to culture <i>Schistosoma mansoni</i> from cercariae to juvenile worm stages for <i>in vitro</i> drug testingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.