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Article

Resolution of Sterile Inflammation: Role for Vitamin C

1 Jan 2014

Abstract excerpt

INTRODUCTION: Macrophage reprogramming is vital for resolution of acute inflammation. Parenteral vitamin C (VitC) attenuates proinflammatory states in murine and human sepsis. However information about the mechanism by which VitC regulates resolution of inflammation is limited. METHODS: To examine whether physiological levels of VitC modulate resolution of inflammation, we used transgenic mice lacking...

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PMID: 25294953
DOI: 10.1155/2014/173403

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