Article
Selenium deficiency abrogates inflammation-dependent plasma cell tumors in mice.
Cancer research - 15 Apr 2004
Felix Klaus, Gerstmeier Simone, Kyriakopoulos Antonios, Howard O M Zack, Dong Hui-Fang, Eckhaus Michael, Behne Dietrich, Bornkamm Georg W, Janz Siegfried
Abstract excerpt
The role of the micronutrient, selenium, in human cancers associated with chronic inflammations and persistent infections is poorly understood. Peritoneal plasmacytomas (PCTs) in strain BALB/c (C), the premier experimental model of inflammation-dependent plasma cell transformation in mice, may afford an opportunity to gain additional insights into the significance of selenium in neoplastic development. Here, we...
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