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Article

Enhanced cellular uptake of antisecretory peptide AF-16 through proteoglycan binding.

Biochemistry - 21 Oct 2014

Matson Dzebo Maria, Reymer Anna, Fant Kristina, Lincoln Per, Nordén Bengt, Rocha Sandra

Abstract excerpt

Peptide AF-16, which includes the active site of Antisecretory Factor protein, has antisecretory and anti-inflammatory properties, making it a potent drug candidate for treatment of secretory and inflammatory diseases such as diarrhea, inflammatory bowel diseases, and intracranial hypertension. Despite remarkable physiological effects and great pharmaceutical need for drug discovery, very little is yet understood...

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PMID: 25289567
DOI: 10.1021/bi5010377

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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