Molecular alterations in non-small cell lung carcinomas of the young.

doi:10.1016/j.humpath.2014.08.005

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Article

Molecular alterations in non-small cell lung carcinomas of the young.

Human pathology - 1 Dec 2014

VandenBussche Christopher J, Illei Peter B, Lin Ming-Tseh, Ettinger David S, Maleki Zahra

Abstract excerpt

Lung cancer is the leading cause of cancer death in the United States. Gene alterations are significant in lung tumorigenesis, with certain genes (Kristen rat sarcoma viral oncogene homolog (KRAS), epidermal growth factor receptor [EGFR], anaplastic lymphoma kinase [ALK], and B-Raf proto-oncogene...

Topics

Adult
Anaplastic Lymphoma Kinase
Carcinoma, Non-Small-Cell Lung
DNA Mutational Analysis
Databases, Factual
ErbB Receptors
Female
Gene Frequency
Gene Rearrangement
Humans
Lung Neoplasms
Male
Middle Aged
Mutation
Proto-Oncogene Mas
Proto-Oncogene Proteins
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins p21(ras)

Source

Open in PubMed

Identifiers

PMID: 25288236
DOI: 10.1016/j.humpath.2014.08.005

Genes

KRAS
ALK
EGFR
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25288236-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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