Article
Frequent genomic alterations and better prognosis among young patients with non-small-cell lung cancer aged 40 years or younger.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Sept 2018
Pan X, Lv T, Zhang F, Fan H, Liu H, Song Y
Abstract excerpt
BACKGROUND: The subgroup of young patients with non-small-cell lung cancer (NSCLC) is poorly understood. We retrospectively studied the clinical characteristics, gene mutations, and outcomes of patients with NSCLC (aged ≤ 40 years). RESULTS: Of the 7494 patients with lung cancer diagnosed from February 2001 to October 2016, 252 aged ≤ 40 years showed NSCLC. We divided their cases into non-squamous cell carcinoma...
Topics
- Adult
- Anaplastic Lymphoma Kinase
- Carcinoma, Non-Small-Cell Lung
- ErbB Receptors
- Female
- Humans
- Lung Neoplasms
- Male
- Mutation
- Prognosis
- Proto-Oncogene Mas
- Receptor Protein-Tyrosine Kinases
- Retrospective Studies