Article
[Clinical significance of interleukin-28B and RNAse L gene polymorphism determination in patients with chronic viral hepatitis C].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Mitsura V M, Voropaev E V, Osipkina O V, Zhavoronok S V, Tereshkov D V, Baranov O Iu
Abstract excerpt
AIM: Determination of frequency of occurrence and clinical significance ofinterleukin-28B (IL28B) and RNAse L gene polymorphism in patients with chronic hepatitis C (CHC). MATERIALS AND METHODS: 104 hospital patients with CHC (65% male; 63% with genotype 1 hepatitis C virus - HCV) were examined. 70 patients received therapy with interferon (IFN) and ribavirin (RBV). Single nucleotide polymorphism (SNP) of IL28B...
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