Article
IRF5rs2004640 single nucleotide polymorphism is associated with susceptibility to rheumatoid arthritis in South Indian Tamils.
Tissue antigens - 1 Nov 2014
Negi V S, Muralidharan N, Mehra S, Devaraju P, Mariaselvam C M, Gulati R, Salah S, Fortier C, Charron D, Krishnamoorthy R, Tamouza R
Abstract excerpt
Polymorphism of interferon regulatory factor 5 (IRF5), a latent transcription factor gene has been associated with various auto-immune diseases. Our aim was to study the IRF5rs2004640 gene polymorphism and its association with disease susceptibility, disease phenotype and treatment response in South Indian Tamil patients with rheumatoid arthritis (RA).The study was conducted on 217 RA patients fulfilling the...
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