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Article

Risk of false positive genetic associations in complex traits with underlying population structure: a case study.

Veterinary journal (London, England : 1997) - 1 Dec 2014

Finno Carrie J, Aleman Monica, Higgins Robert J, Madigan John E, Bannasch Danika L

Abstract excerpt

Genome-wide association (GWA) studies are widely used to investigate the genetic etiology of diseases in domestic animals. In the horse, GWA studies using 40-50,000 single nucleotide polymorphisms (SNPs) in sample sizes of 30-40 individuals, consisting of only 6-14 affected horses, have led to the discovery of genetic mutations for simple monogenic traits. Equine neuroaxonal dystrophy is a common inherited...

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Identifiers

PMID: 25278384
DOI: 10.1016/j.tvjl.2014.09.013
PMCID: PMC4337777

Genes

RIT2
SYT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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