Article
Genetic mapping of recurrent exertional rhabdomyolysis in a population of North American Thoroughbreds.
Animal genetics - 1 Dec 2012
Fritz K L, McCue M E, Valberg S J, Rendahl A K, Mickelson J R
Abstract excerpt
Recurrent exertional rhabdomyolysis is a heritable disorder that results in painful skeletal muscle cramping with exercise in up to 10% of all Thoroughbred racehorses. Here, we report a genome-wide association study with 48 282 SNPs analyzed among 48 case and 37 control Thoroughbreds. The most significant SNPs spanned approximately 13 Mb on ECA16, and the P-value of the most significant SNP after correcting for...
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