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Article

Prospects for gene-environment interactions in exfoliation syndrome.

Journal of glaucoma - 1 Jan 2000

Pasquale Louis R, Kang Jae H, Wiggs Janey L

Abstract excerpt

Complex traits can be triggered by environmental factors in genetically predisposed individuals. The lysyl oxidase-like 1 gene (LOXL1) variants associated with exfoliation syndrome (XFS) are detected in >90% of cases that have been genotyped from sites around the world. Remarkably, roughly 80% of people without XFS also possess these same variants in all populations that have been tested. Nonetheless, the...

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Source

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Identifiers

PMID: 25275911
DOI: 10.1097/IJG.0000000000000113
PMCID: PMC8092031

Genes

LOXL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prospects for gene-environment interactions in exfoliation syndrome.PMID 25275911Read ↗

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Evaluation of LOXL1 gene polymorphisms in exfoliation syndrome and exfoliation glaucoma.Semantic proximity Read ↗

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Evaluation of LOXL1 polymorphisms in exfoliation syndrome in the Uygur population.Semantic proximity Read ↗

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