Article
Immune biomarkers predictive of respiratory viral infection in elderly nursing home residents.
PloS one - 1 Jan 2014
Johnstone Jennie, Parsons Robin, Botelho Fernando, Millar Jamie, McNeil Shelly, Fulop Tamas, McElhaney Janet, Andrew Melissa K, Walter Stephen D, Devereaux P J, Malekesmaeili Mehrnoush, Brinkman Ryan R, Mahony James, Bramson Jonathan, Loeb Mark
Abstract excerpt
OBJECTIVE: To determine if immune phenotypes associated with immunosenescence predict risk of respiratory viral infection in elderly nursing home residents. METHODS: Residents ≥ 65 years from 32 nursing homes in 4 Canadian cities were enrolled in Fall 2009, 2010 and 2011, and followed for one influenza season. Following influenza vaccination, peripheral blood mononuclear cells (PBMCs) were obtained and analysed...
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