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Article

Immune resilience in HIV-infected individuals seronegative for cytomegalovirus.

AIDS (London, England) - 10 Sept 2014

Barrett Lisa, Stapleton Staci N, Fudge Neva J, Grant Michael D

Abstract excerpt

OBJECTIVE: Low CD4/CD8 T-cell ratios occur in conditions associated with reduced immune resilience, including older age and HIV infection. Effective antiretroviral therapy increases CD4/CD8 T-cell ratios, but often not to preinfection levels. The reasons for this deficit remain unclear. As cytomegalovirus (CMV) infection exacerbates falling CD4/CD8 T-cell ratios and immune senescence in the old elderly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25265072
DOI: 10.1097/QAD.0000000000000405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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