Article
Relationship between a frailty-related phenotype and progressive deterioration of the immune system in HIV-infected men.
Journal of acquired immune deficiency syndromes (1999) - 1 Mar 2009
Desquilbet Loic, Margolick Joseph B, Fried Linda P, Phair John P, Jamieson Beth D, Holloway Marcy, Jacobson Lisa P
Abstract excerpt
CONTEXT: Immunological similarities have been noted between HIV-infected individuals and older HIV-negative adults. Immunologic alterations with aging have been noted in frailty in older adults, a clinical syndrome of high risk for mortality and other adverse outcomes. Using a frailty-related phenotype (FRP), we investigated in the Multicenter AIDS Cohort Study whether progressive deterioration of the immune...
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